Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity

Natural Killer cells are innate lymphocytes with central roles in immunosurveillance and are implicated in autoimmune pathogenesis. The degree to which regulatory variants affect Natural Killer cell gene expression is poorly understood. Here we perform expression quantitative trait locus mapping of...

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Bibliographic Details
Main Authors: Gilchrist, JJ, Makino, S, Naranbhai, V, Sharma, PK, Koturan, S, Tong, O, Taylor, CA, Watson, RA, de Los Aires, AV, Cooper, R, Lau, E, Danielli, S, Hameiri-Bowen, D, Lee, W, Ng, E, Whalley, J, Knight, JC, Fairfax, BP
Format: Journal article
Language:English
Published: Springer Nature 2022