Ex vivo interferon-gamma immune response to thrombospondin-related adhesive protein in coastal Kenyans: longevity and risk of Plasmodium falciparum infection.

Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum is currently being tested in human vaccine studies. However, its natural reactivity in the field remains poorly characterized. More than 40% of 217 Kenyan donors responded in an ex vivo interferon-gamma (IFN-gamma) enzyme-linked...

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Bibliographic Details
Main Authors: Flanagan, K, Mwangi, T, Plebanski, M, Odhiambo, K, Ross, A, Sheu, E, Kortok, M, Lowe, B, Marsh, K, Hill, A
Format: Journal article
Language:English
Published: 2003