Co-operative additive effects between HLA alleles in control of HIV-1

Background HLA class I genotype is a major determinant of the outcome of HIV infection, and the impact of certain alleles on HIV disease outcome is well studied. Recent studies have demonstrated that certain HLA class I alleles that are in linkage disequilibrium, such as HLA-A*74 and HLA-B*57, appea...

Full description

Bibliographic Details
Main Authors: Matthews, P, Listgarten, J, Carlson, J, Payne, R, Huang, K, Frater, J, Goedhals, D, Steyn, D, Van Vuuren, C, Paioni, P, Jooste, P, Ogwu, A, Shapiro, R, Mncube, Z, Ndung'U, T, Walker, B, Heckerman, D, Goulder, P
Format: Journal article
Language:English
Published: Public Library of Science 2012