Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120.

It is well established that the gp120 V3 loop of T-cell-line-adapted human immunodeficiency virus type 1 (HIV-1) binds both cell-associated and soluble polyanions. Virus infectivity is increased by interactions between HIV-1 and heparan sulfate proteoglycans on some cell types, and soluble polyanion...

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Bibliographic Details
Main Authors: Moulard, M, Lortat-Jacob, H, Mondor, I, Roca, G, Wyatt, R, Sodroski, J, Zhao, L, Olson, W, Kwong, P, Sattentau, Q
Format: Journal article
Language:English
Published: 2000