Autophagosome proteins LC3A, LC3B and LC3C have distinct subcellular distribution kinetics and expression in cancer cell lines

LC3s (MAP1-LC3A, B and C) are structural proteins of autophagosomal membranes, widely used as biomarkers of autophagy. Whether these three LC3 proteins have a similar biological role in autophagy remains obscure. We examine in parallel the subcellular expression patterns of the three LC3 proteins in...

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Bibliographic Details
Main Authors: Koukourakis, M, Kalamida, D, Giatromanolaki, A, Zois, C, Sivridis, E, Pouliliou, S, Mitrakas, A, Gatter, K, Harris, A
Format: Journal article
Language:English
Published: Public Library of Science 2015