Association of a polymorphism in the P2X7 gene with tuberculosis in a Gambian population.
Adenosine triphosphate (ATP) ligation of P2X(7) receptors expressed on human macrophages that are infected with mycobacteria induces cell death and subsequent loss of intracellular bacterial viability. Marked heterogeneity observed in cell donor ATP responsiveness suggests that this antimycobacteria...
| Main Authors: | , , , , , , , |
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| Format: | Conference item |
| Published: |
2002
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