Modelling medulloblastoma using cerebellar organoids

<p>Medulloblastoma (MB) is the most common malignant brain tumour in children and originates from cerebellar progenitor cells. Although extensive genomic studies have resulted in detailed molecular signatures of MB subtypes, current preclinical models often fail to capture human tumour biology...

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Bibliographic Details
Main Author: van Essen, MJ
Other Authors: Becker, E
Format: Thesis
Language:English
Published: 2022
Subjects: