NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis.

Neuropilin (NRP) 1 is a receptor for the vascular endothelial growth factor (VEGF)-A and is essential for normal angiogenesis. Previous in vitro experiments identified NRP1 interactions with VEGF-A's main signaling receptor VEGFR2 within endothelial cells, but also between nonendothelial NRP1 a...

Full description

Bibliographic Details
Main Authors: Fantin, A, Vieira, J, Plein, A, Denti, L, Fruttiger, M, Pollard, J, Ruhrberg, C
Format: Journal article
Language:English
Published: 2013