NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis.
Neuropilin (NRP) 1 is a receptor for the vascular endothelial growth factor (VEGF)-A and is essential for normal angiogenesis. Previous in vitro experiments identified NRP1 interactions with VEGF-A's main signaling receptor VEGFR2 within endothelial cells, but also between nonendothelial NRP1 a...
Main Authors: | Fantin, A, Vieira, J, Plein, A, Denti, L, Fruttiger, M, Pollard, J, Ruhrberg, C |
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Format: | Journal article |
Language: | English |
Published: |
2013
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