Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies

Several studies have confirmed α-synuclein real-time quaking-induced conversion (αSyn-RT-QuIC) assay to have high sensitivity and specificity for Parkinson’s disease. However, whether the assay can be used as a robust, quantitative measure to monitor disease progression, stratify different synuclein...

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Bibliographic Details
Main Authors: Poggiolini, I, Gupta, V, Lawton, M, Lee, S, El-Turabi, A, Querejeta-Coma, A, Trenkwalder, C, Sixel-Döring, F, Foubert-Samier, A, Le Traon, AP, Plazzi, G, Biscarini, F, Montplaisir, J, Gagnon, J-F, Postuma, RB, Antelmi, E, Meissner, WG, Mollenhauer, B, Ben-Shlomo, Y, Hu, MT, Parkkinen, L
Format: Journal article
Language:English
Published: Oxford University Press 2021