Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies
Several studies have confirmed α-synuclein real-time quaking-induced conversion (αSyn-RT-QuIC) assay to have high sensitivity and specificity for Parkinson’s disease. However, whether the assay can be used as a robust, quantitative measure to monitor disease progression, stratify different synuclein...
Autori principali: | Poggiolini, I, Gupta, V, Lawton, M, Lee, S, El-Turabi, A, Querejeta-Coma, A, Trenkwalder, C, Sixel-Döring, F, Foubert-Samier, A, Le Traon, AP, Plazzi, G, Biscarini, F, Montplaisir, J, Gagnon, J-F, Postuma, RB, Antelmi, E, Meissner, WG, Mollenhauer, B, Ben-Shlomo, Y, Hu, MT, Parkkinen, L |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
Oxford University Press
2021
|
Documenti analoghi
Documenti analoghi
-
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
di: Parkkinen, L, et al.
Pubblicazione: (2016) -
Investigating brain-derived α-synuclein fibrils and diagnostic biomarkers of synucleinopathies
di: Lee, S
Pubblicazione: (2023) -
LRP10 in α-synucleinopathies
di: Guerreiro, R, et al.
Pubblicazione: (2018) -
LRRK2 protective haplotype and full sequencing study in REM sleep behavior disorder
di: Ouled Amar Bencheikh, B, et al.
Pubblicazione: (2018) -
Selective vulnerability in α-synucleinopathies.
di: Alegre-Abarrategui, J, et al.
Pubblicazione: (2019)