Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly.

OBJECTIVE: Patients with acromegaly are at increased risk of developing colorectal carcinoma and premalignant tubulovillous adenoma. The pathogenesis of these neoplasms could involve a stimulatory effect of serum growth factors on colonic epithelial cell proliferation. The aim of this study was to e...

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Bibliographic Details
Main Authors: Miraki-Moud, F, Jenkins, P, Fairclough, P, Jordan, S, Bustin, SA, Jones, A, Lowe, D, Monson, J, Grossman, AB, Besser, G, Camacho-Hübner, C
Format: Journal article
Language:English
Published: 2001