Therapeutic implications of GIPC1 silencing in cancer.

GIPC1 is a cytoplasmic scaffold protein that interacts with numerous receptor signaling complexes, and emerging evidence suggests that it plays a role in tumorigenesis. GIPC1 is highly expressed in a number of human malignancies, including breast, ovarian, gastric, and pancreatic cancers. Suppressio...

Full description

Bibliographic Details
Main Authors: Chittenden, T, Pak, J, Rubio, R, Cheng, H, Holton, K, Prendergast, N, Glinskii, V, Cai, Y, Culhane, A, Bentink, S, Schwede, M, Mar, J, Howe, E, Aryee, M, Sultana, R, Lanahan, A, Taylor, J, Holmes, C, Hahn, W, Zhao, J, Iglehart, J, Quackenbush, J
Format: Journal article
Language:English
Published: Public Library of Science 2010