Interferon regulatory factor-1 polymorphisms are associated with the control of Plasmodium falciparum infection.

We describe the haplotypic structure of the interferon regulatory factor-1 (IRF-1) locus in two West African ethnic groups, Fulani and Mossi, that differ in their susceptibility and immune response to Plasmodium falciparum malaria. Both populations showed significant associations between IRF-1 polym...

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Bibliographic Details
Main Authors: Mangano, V, Luoni, G, Rockett, K, Sirima, B, Konaté, A, Forton, J, Clark, T, Bancone, G, Sadighi Akha, E, Akha, E, Kwiatkowski, D, Modiano, D
Format: Journal article
Language:English
Published: 2008