Mass spectrometric assays reveal discrepancies in inhibition profiles for the SARS-CoV-2 papain-like protease
The two SARS-CoV-2 proteases, i.e. the main protease (Mpro) and the papain-like protease (PLpro), which hydrolyze the viral polypeptide chain giving functional non-structural proteins, are essential for viral replication and are medicinal chemistry targets. We report a high-throughput mass spectrome...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Wiley
2022
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