Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
Salmonella Typhi is a human host-restricted pathogen that is responsible for typhoid fever in approximately 10.9 million people annually1. The typhoid toxin is postulated to have a central role in disease pathogenesis, the establishment of chronic infection and human host restriction2-6. However, it...
Main Authors: | Gibani, M, Jones, E, Barton, A, Jin, C, Meek, J, Camara, S, Galal, U, Heinz, E, Rosenberg-Hasson, Y, Obermoser, G, Jones, C, Campbell, D, Black, C, Thomaides-Brears, H, Darlow, C, Dold, C, Silva-Reyes, L, Blackwell, L, Lara-Tejero, M, Jiao, X, Stack, G, Blohmke, C, Hill, J, Angus, B, Dougan, G, Galán, J, Pollard, A |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2019
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