Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
Salmonella Typhi is a human host-restricted pathogen that is responsible for typhoid fever in approximately 10.9 million people annually1. The typhoid toxin is postulated to have a central role in disease pathogenesis, the establishment of chronic infection and human host restriction2-6. However, it...
Main Authors: | Gibani, M, Jones, E, Barton, A, Jin, C, Meek, J, Camara, S, Galal, U, Heinz, E, Rosenberg-Hasson, Y, Obermoser, G, Jones, C, Campbell, D, Black, C, Thomaides-Brears, H, Darlow, C, Dold, C, Silva-Reyes, L, Blackwell, L, Lara-Tejero, M, Jiao, X, Stack, G, Blohmke, C, Hill, J, Angus, B, Dougan, G, Galán, J, Pollard, A |
---|---|
格式: | Journal article |
語言: | English |
出版: |
Springer Nature
2019
|
相似書籍
-
Typhoid fever.
由: Parry, C, et al.
出版: (2002) -
Salmonella typhi bactericidal antibodies reduce disease severity but do not protect against typhoid fever in a controlled human infection model
由: Juel, H, et al.
出版: (2018) -
Molecular correlates of vaccine-induced protection against typhoid fever
由: Zhu, H, et al.
出版: (2023) -
Typhoid and paratyphoid fever: a call to action
由: Gibani, M, et al.
出版: (2018) -
Typhoid epidemiology, diagnostics and the human challenge model.
由: Darton, T, et al.
出版: (2014)