Use of BODIPY-cholesterol (TF-Chol) for visualizing lysosomal cholesterol accumulation

Dipyrromethene difluoride-cholesterol (TopFluor-Cholesterol, TF-Chol) is a widely used cholesterol analogue due to its excellent fluorescence properties and considerable similarity with natural cholesterol in terms of membrane partitioning. However, the suitability of TF-Chol for detecting lysosomal...

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Bibliographic Details
Main Authors: Hölttä-Vuori, M, Sezgin, E, Eggeling, C, Ikonen, E
Format: Journal article
Language:English
Published: Wiley 2016