A high throughput screen for next-generation leads targeting malaria parasite transmission

Spread of parasite resistance to artemisinin threatens current frontline antimalarial therapies, highlighting the need for new drugs with alternative modes of action. Since only 0.2-1% of asexual parasites differentiate into sexual, transmission-competent forms, targeting this natural bottleneck pro...

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Bibliographic Details
Main Authors: Delves, MJ, Miguel-Blanco, C, Matthews, H, Molina, I, Ruecker, A, Yahiya, S, Straschil, U, Abraham, M, León, ML, Fischer, OJ, Rueda-Zubiaurre, A, Brandt, JR, Cortés, Á, Barnard, A, Fuchter, MJ, Calderón, F, Winzeler, EA, Sinden, RE, Herreros, E, Gamo, FJ, Baum, J
Format: Journal article
Language:English
Published: Nature Publishing Group 2018