High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability

Interest in reconstructing demographic histories has motivated the development of methods to estimate locus-specific pairwise coalescence times from whole-genome sequencing data. Here we introduce a powerful new method, ASMC, that can estimate coalescence times using only SNP array data, and is orde...

Full description

Bibliographic Details
Main Authors: Palamara, P, Terhorst, J, Song, Y, Price, A
Format: Journal article
Published: Nature Publishing Group 2018