High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability

Interest in reconstructing demographic histories has motivated the development of methods to estimate locus-specific pairwise coalescence times from whole-genome sequencing data. Here we introduce a powerful new method, ASMC, that can estimate coalescence times using only SNP array data, and is orde...

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Bibliografiska uppgifter
Huvudupphovsmän: Palamara, P, Terhorst, J, Song, Y, Price, A
Materialtyp: Journal article
Publicerad: Nature Publishing Group 2018