Progress and outlook in studying the substrate specificities of PARPs and related enzymes

Despite decades of research on ADP‐ribosyltransferases (ARTs) from the poly(ADP‐ribose) polymerase (PARP) family, one key aspect of these enzymes – their substrate specificity – has remained unclear. Here, we briefly discuss the history of this area and, more extensively, the recent breakthroughs, i...

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Detalhes bibliográficos
Principais autores: Suskiewicz, MJ, Palazzo, L, Hughes, R, Ahel, I
Formato: Journal article
Idioma:English
Publicado em: Wiley 2020