Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.
BACKGROUND: Var genes encode a family of virulence factors known as PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1) which are responsible for both antigenic variation and cytoadherence of infected erythrocytes. Although these molecules play a central role in malaria pathogenesis, the...
| Autori principali: | , , , , , , , , , , , |
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| Altri autori: | |
| Natura: | Journal article |
| Lingua: | English |
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BioMed Central
2007
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