Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.

BACKGROUND: Var genes encode a family of virulence factors known as PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1) which are responsible for both antigenic variation and cytoadherence of infected erythrocytes. Although these molecules play a central role in malaria pathogenesis, the...

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Detaylı Bibliyografya
Asıl Yazarlar:	Kraemer, S, Kyes, SA, Aggarwal, G, Springer, A, Nelson, S, Christodoulou, Z, Smith, L, Wang, W, Levin, E, Newbold, C, Myler, P, Smith, J
Diğer Yazarlar:	Broad Institute
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	BioMed Central 2007

Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.

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