Suppression of enhancer overactivation by a RACK7-Histone demethylase complex

Regulation of enhancer activity is important for controlling gene expression programs. Here, we report that a biochemical complex containing a potential chromatin reader, RACK7, and the histone lysine 4 tri-methyl (H3K4me3)-specific demethylase KDM5C occupies many active enhancers, including almost...

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Bibliographic Details
Main Authors: Shen, H, Xu, W, Guo, R, Rong, B, Gu, L, Wang, Z, He, C, Zheng, L, Hu, X, Hu, Z, Shao, Z-M, Yang, P, Wu, F, Shi, YG, Lan, F, Shi, Y
Format: Journal article
Language:English
Published: Cell Press 2016