Ion mobility-mass spectrometry reveals the influence of subunit packing and charge on the dissociation of multiprotein complexes.

The composition, stoichiometry, and organization of protein complexes can be determined by collision-induced dissociation (CID) coupled to tandem mass spectrometry (MS/MS). The increased use of this approach in structural biology prompts a better understanding of the dissociation mechanism(s). Here...

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Bibliographic Details
Main Authors: Boeri Erba, E, Ruotolo, B, Barsky, D, Robinson, C
Format: Journal article
Language:English
Published: 2010