Looking for therapeutic antibodies in next-generation sequencing repositories

Recently it has become possible to query the great diversity of natural antibody repertoires using next-generation sequencing (NGS). These methods are capable of producing millions of sequences in a single experiment. Here we compare clinical-stage therapeutic antibodies to the ~1b sequences from 60...

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Bibliographic Details
Main Authors: Krawczyk, K, Raybould, M, Kovaltsuk, A, Deane, C
Format: Journal article
Published: Taylor and Francis 2019