Looking for therapeutic antibodies in next-generation sequencing repositories

Recently it has become possible to query the great diversity of natural antibody repertoires using next-generation sequencing (NGS). These methods are capable of producing millions of sequences in a single experiment. Here we compare clinical-stage therapeutic antibodies to the ~1b sequences from 60...

Полное описание

Библиографические подробности
Главные авторы: Krawczyk, K, Raybould, M, Kovaltsuk, A, Deane, C
Формат: Journal article
Опубликовано: Taylor and Francis 2019