Altered plasma glutathione levels in bipolar disorder indicates higher oxidative stress; a possible risk factor for illness onset despite normal brain-derived neurotrophic factor (BDNF) levels.

BACKGROUND: Oxidative stress and neurotrophic factors have been implicated in the pathophysiology of bipolar disorder. Our objective was to determine whether plasma glutathione or brain-derived neurotrophic factor (BDNF) levels were abnormal in bipolar disorder and therefore useful as possible bioma...

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Bibliographic Details
Main Authors: Rosa, A, Singh, N, Whitaker, E, de Brito, M, Lewis, A, Vieta, E, Churchill, G, Geddes, J, Goodwin, G
Format: Journal article
Language:English
Published: Cambridge University Press 2014