Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells.

Interleukin 4 (IL-4) has previously been shown to downregulate the production of proinflammatory cytokines such as TNF-alpha, and hence has been considered to be a potential anti-inflammatory agent. In this study we have investigated the effects of IL-4 on the expression of both p55 and p75 TNF rece...

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Dettagli Bibliografici
Autori principali: Cope, A, Gibbons, D, Aderka, D, Foxwell, B, Wallach, D, Maini, R, Feldmann, M, Brennan, F
Natura: Journal article
Lingua:English
Pubblicazione: 1993