The role of RAS mutations in MLL-rearranged leukaemia: a path to intervention?

Childhood acute lymphoblastic leukaemia (ALL) with MLL rearrangement (MLL-r) is an aggressive disease still associated with a high mortality rate. Recent investigations have identified co-operating mutations in the RAS pathway and although the functional consequences of these mutations are not yet f...

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Bibliographic Details
Main Authors: Mansur, MB, Ford, AM, Emerenciano, M
Format: Journal article
Language:English
Published: Elsevier 2017