The role of RAS mutations in MLL-rearranged leukaemia: a path to intervention?
Childhood acute lymphoblastic leukaemia (ALL) with MLL rearrangement (MLL-r) is an aggressive disease still associated with a high mortality rate. Recent investigations have identified co-operating mutations in the RAS pathway and although the functional consequences of these mutations are not yet f...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2017
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