EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV.

We evaluated the efficacy of equine infectious anaemia virus (EIAV)-based lentiviral vectors encoding endostatin (EIAV.endostatin) or angiostatin (EIAV.angiostatin) in inhibiting angiogenesis and vascular hyperpermeability in the laser-induced model of choroidal neovascularisation (CNV). Equine infe...

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Bibliographic Details
Main Authors: Balaggan, K, Binley, K, Esapa, M, Maclaren, R, Iqball, S, Duran, Y, Pearson, R, Kan, O, Barker, SE, Smith, A, Bainbridge, J, Naylor, S, Ali, R
Format: Journal article
Language:English
Published: 2006