Non-invasive multiphoton imaging of islets transplanted Into the pinna of the NOD mouse ear reveals the immediate effect of anti-CD3 treatment in autoimmune diabetes

We present a novel and readily accessible method facilitating cellular time-resolved imaging of transplanted pancreatic islets. Grafting of islets to the mouse ear pinna allows non-invasive, in vivo longitudinal imaging of events in the islets and enables improved acquisition of experimental data a...

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Bibliographic Details
Main Authors: Benson, RA, Garcon, F, Recino, A, Ferdinand, JR, Clatworthy, MR, Waldmann, H, Brewer, JM, Okkenhaug, K, Cooke, A, Garside, P, Wallberg, M
Format: Journal article
Published: Frontiers Media 2018