The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040.

1. Following our earlier observations that the tachykinin NK1 receptor antagonist CP-99,994 is an effective anti-emetic in ferrets, we have examined the anti-emetic effects of a more potent and novel NK1 receptor antagonist, GR203040, against various emetic stimuli in the ferret, dog and house musk...

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Bibliographic Details
Main Authors: Gardner, C, Twissell, D, Dale, T, Gale, J, Jordan, C, Kilpatrick, G, Bountra, C, Ward, P
Format: Journal article
Language:English
Published: 1995