Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures

Despite the conventional view that a truly random V(D)J recombination process should generate a highly diverse immune repertoire, emerging reports suggest that there is a certain bias toward the generation of shared/public immune receptor chains. These studies were performed in viral diseases where...

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Bibliographic Details
Main Authors: Teng, YHF, Quah, HS, Suteja, L, Dias, JML, Mupo, A, Bashford-Rogers, RJM, Vassiliou, GS, Chua, MLK, Tan, DSW, Lim, DWT, Iyer, NG
Format: Journal article
Language:English
Published: Springer Nature 2021