Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose.

Glucose-inhibited neurons orchestrate behavior and metabolism according to body energy levels, but how glucose inhibits these cells is unknown. We studied glucose inhibition of orexin/hypocretin neurons, which promote wakefulness (their loss causes narcolepsy) and also regulate metabolism and reward...

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Détails bibliographiques
Auteurs principaux: Burdakov, D, Jensen, LT, Alexopoulos, H, Williams, R, Fearon, I, O'Kelly, I, Gerasimenko, O, Fugger, L, Verkhratsky, A
Format: Journal article
Langue:English
Publié: 2006