Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose.

Glucose-inhibited neurons orchestrate behavior and metabolism according to body energy levels, but how glucose inhibits these cells is unknown. We studied glucose inhibition of orexin/hypocretin neurons, which promote wakefulness (their loss causes narcolepsy) and also regulate metabolism and reward...

Full description

Bibliographic Details
Main Authors: Burdakov, D, Jensen, LT, Alexopoulos, H, Williams, R, Fearon, I, O'Kelly, I, Gerasimenko, O, Fugger, L, Verkhratsky, A
Format: Journal article
Language:English
Published: 2006