Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose.
Glucose-inhibited neurons orchestrate behavior and metabolism according to body energy levels, but how glucose inhibits these cells is unknown. We studied glucose inhibition of orexin/hypocretin neurons, which promote wakefulness (their loss causes narcolepsy) and also regulate metabolism and reward...
Main Authors: | Burdakov, D, Jensen, LT, Alexopoulos, H, Williams, R, Fearon, I, O'Kelly, I, Gerasimenko, O, Fugger, L, Verkhratsky, A |
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Format: | Journal article |
Language: | English |
Published: |
2006
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