Antigen-specific T-cell downregulation by human dendritic cells following blockade of NF-kappaB.

Dendritic cells (DCs) are important for presenting antigen to T cells, especially naïve T cells. It has recently been shown that blocking the transcription factor, nuclear factor kappa B (NF-kappaB) in human DCs inhibited the mixed leukocyte reaction. The aim of this study was to investigate the eff...

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Bibliographic Details
Main Authors: Calder, V, Bondeson, J, Brennan, F, Foxwell, B, Feldmann, M
Format: Journal article
Language:English
Published: 2003