Antigen-specific T-cell downregulation by human dendritic cells following blockade of NF-kappaB.
Dendritic cells (DCs) are important for presenting antigen to T cells, especially naïve T cells. It has recently been shown that blocking the transcription factor, nuclear factor kappa B (NF-kappaB) in human DCs inhibited the mixed leukocyte reaction. The aim of this study was to investigate the eff...
Hoofdauteurs: | Calder, V, Bondeson, J, Brennan, F, Foxwell, B, Feldmann, M |
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Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
2003
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