The mammalian endoplasmic reticulum-associated degradation system.

The endoplasmic reticulum (ER) is the site of synthesis for nearly one-third of the eukaryotic proteome and is accordingly endowed with specialized machinery to ensure that proteins deployed to the distal secretory pathway are correctly folded and assembled into native oligomeric complexes. Proteins...

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Bibliographic Details
Main Authors: Olzmann, J, Kopito, R, Christianson, J
Format: Journal article
Language:English
Published: 2013