The mammalian endoplasmic reticulum-associated degradation system.

The endoplasmic reticulum (ER) is the site of synthesis for nearly one-third of the eukaryotic proteome and is accordingly endowed with specialized machinery to ensure that proteins deployed to the distal secretory pathway are correctly folded and assembled into native oligomeric complexes. Proteins...

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Main Authors: Olzmann, J, Kopito, R, Christianson, J
格式: Journal article
语言:English
出版: 2013