Modulation of the effects of tropomyosin on actin and myosin conformational changes by troponin and Ca2+.

The molecular mechanisms by which troponin (TN)-tropomyosin (TM) regulates the myosin ATPase cycle were investigated using fluorescent probes specifically bound to Cys36 of TM, Cys707 of myosin subfragment-1, and Cys374 of actin incorporated into ghost muscle fibers. Intermediate states of actomyosi...

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Bibliographic Details
Main Authors: Borovikov, Y, Karpicheva, O, Avrova, S, Redwood, C
Format: Journal article
Language:English
Published: 2009