Modulation of the effects of tropomyosin on actin and myosin conformational changes by troponin and Ca2+.
The molecular mechanisms by which troponin (TN)-tropomyosin (TM) regulates the myosin ATPase cycle were investigated using fluorescent probes specifically bound to Cys36 of TM, Cys707 of myosin subfragment-1, and Cys374 of actin incorporated into ghost muscle fibers. Intermediate states of actomyosi...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2009
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