Association between impaired vα7.2+cd161++cd8+ (MAIT) and vα7.2+cd161-cd8+ t-cell populations and gut dysbiosis in chronically HIV-and/or HCV-infected patients
Both HIV and HCV infections feature increased microbial translocation (MT) and gut dysbiosis that affect immune homeostasis and disease outcome. Given their commitment to antimicrobial mucosal immunity, we investigated mucosal-associated invariant T (MAIT) cells and Vα7.2+CD161-T-cell frequency/func...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Published: |
Frontiers Media
2019
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