Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity.
BACKGROUND: When assessing the efficacy of gene transfer agents (GTAs) for cystic fibrosis (CF) gene therapy, we routinely evaluate gene transfer in the mouse nose and measure transfection efficiency by assessing transgene-specific mRNA using the real-time (TaqMan) quantitative reverse transcriptase...
Κύριοι συγγραφείς: | Holder, E, Stevenson, B, Farley, R, Hilliard, T, Wodehouse, T, Somerton, L, Larsen, M, O'Donoghue, J, Coles, R, Scheule, R, Cheng, S, Gill, DR, Hyde, S, Griesenbach, U, Alton, E, Porteous, D, Boyd, A |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2010
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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SAFETY AND EXPRESSION OF A SINGLE DOSE OF LIPID-MEDIATED CFTR GENE THERAPY TO THE UPPER AND LOWER AIRWAYS OF PATIENTS WITH CYSTIC FIBROSIS
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Sendai virus-mediated CFTR gene transfer to the airway epithelium.
ανά: Ferrari, S, κ.ά.
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Self-reactive CFTR T cells in humans: implications for gene therapy.
ανά: Calcedo, R, κ.ά.
Έκδοση: (2013)