Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

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OBJECTIVES:Microsatellite instability (MSI) is an established marker of good prognosis in colorectal cancer (CRC). Chromosomal instability (CIN) is strongly negatively associated with MSI and has been shown to be a marker of poor prognosis in a small number of studies. However, a substantial group o...

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Bibliographic Details
Main Authors: Mouradov, D, Domingo, E, Gibbs, P, Jorissen, R, Li, S, Soo, P, Lipton, L, Desai, J, Danielsen, H, Oukrif, D, Novelli, M, Yau, C, Holmes, C, Jones, I, McLaughlin, S, Molloy, P, Hawkins, N, Ward, R, Midgely, R, Kerr, D, Tomlinson, I, Sieber, O
Format: Journal article
Language:English
Published: 2013

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