Structure-function studies for in vitro chemical inhibition of Fc gamma receptor-mediated phagocytosis.

BACKGROUND: Previous studies [Transfusion 2005;45:384] showed that certain chemical compounds containing sulfur-reactive groups can inhibit Fcgamma receptor (FcgammaR)-mediated phagocytosis in vitro. These studies, however, did not prove that only sulfur functionality-induced reactivity was efficac...

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Bibliographic Details
Main Authors: Foo, A, Fletcher, S, Langler, R, Porter, C, Branch, DR
Format: Journal article
Language:English
Published: 2007