Extension of hydrogen borrowing alkylation reactions for the total synthesis of (–)-γ-lycorane
The total synthesis of (–)-γ-lycorane (10 steps) and synthesis of (±)- γ-lycorane (8 steps) was completed from cyclohexenone. A new two step hydrogen borrowing alkylation of an aziridinyl alcohol, coupled with a Ph* deprotection/cyclisation procedure was developed for de novo formation of the fused...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2022
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