Chromatin condensation fluctuations rather than steady-state predict chromatin accessibility

Chromatin accessibility to protein factors is critical for genome activities. However, the dynamic properties of chromatin higher-order structures that regulate its accessibility are poorly understood. Here, we took advantage of the microenvironment sensitivity of the fluorescence lifetime of EGFP-H...

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Hlavní autoři: Audugé, N, Padilla-Parra, S, Tramier, M, Borghi, N, Coppey-Moisan, M
Médium: Journal article
Jazyk:English
Vydáno: Oxford University Press 2019