A hydrophobic gate in an ion channel: the closed state of the nicotinic acetylcholine receptor.
The nicotinic acetylcholine receptor (nAChR) is the prototypic member of the 'Cys-loop' superfamily of ligand-gated ion channels which mediate synaptic neurotransmission, and whose other members include receptors for glycine, gamma-aminobutyric acid and serotonin. Cryo-electron microscopy...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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