Expression profiling of constitutive mast cells reveals a unique identity within the immune system

Mast cells are evolutionarily ancient sentinel cells. Like basophils, mast cells express the high-affinity receptor for immunoglobulin E (IgE) and have been linked to host defense and diverse immune-system-mediated diseases. To better characterize the function of these cells, we assessed the transcr...

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Bibliographic Details
Main Authors: Dwyer, D, Barrett, N, Austen, K, Kim, E, Brenner, M, Shaw, L, Yu, B, Goldrath, A, Mostafavi, S, Regev, A, Rhoades, A, Moodley, D, Yoshida, H, Mathis, D, Benoist, C, Nabekura, T, Lam, V, Lanier, L, Brown, B, Merad, M, Cremasco, V, Turley, S, Monach, P, Dustin, M, Li, Y, Shinton, S, Hardy, R, Shay, T, Qi, Y, Sylvia, K, Kang, J, Fairfax, K, Randolph, G, Robinette, M, Fuchs, A, Colonna, M
Format: Journal article
Published: Nature Publishing Group 2016