Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila
Alternative mRNA splicing adds a layer of regulation to the expression of thousands of genes in Drosophila melanogaster. Not all alternative splicing results in functional protein; it can also yield mRNA isoforms with premature stop codons that are degraded by the nonsense-mediated mRNA decay (NMD)...
Main Authors: | Hansen, K, Lareau, L, Blanchette, M, Green, R, Meng, Q, Rehwinkel, J, Gallusser, F, Izaurralde, E, Rio, D, Dudoit, S, Brenner, SE |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2009
|
Similar Items
-
Nonsense-mediated mRNA decay: Target genes and functional diversification of effectors.
by: Rehwinkel, J, et al.
Published: (2006) -
Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets.
by: Rehwinkel, J, et al.
Published: (2005) -
A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay.
by: Behm-Ansmant, I, et al.
Published: (2007) -
Perspective in Alternative Splicing Coupled to Nonsense-Mediated mRNA Decay
by: Juan F. García-Moreno, et al.
Published: (2020-12-01) -
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay
by: Thomas D Baird, et al.
Published: (2018-03-01)